Hydroxyapatite is a naturally occurring mineral form of calcium apatite, primarily found in bones and teeth. Its chemical formula indicates that it comprises calcium, phosphate, and hydroxyl ions, making it a crucial component for skeletal health and integrity. Hydroxyapatite is known for its excellent biocompatibility and bioactivity. Additionally, this mineral is important in remediating dental caries and enhancing remineralization processes.
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Hydroxyapatite (HA) is a naturally occurring mineral form of calcium apatite. Its chemical formula is generally represented as Ca5HO13P3. Hydroxyapatite is a key component of bone and teeth, providing structural strength and stability due to its crystalline structure. HA is found in the mineralized tissues of vertebrates, making up about 70% of bone by weight and 90% of the inorganic component of teeth.
Biocompatibility
Hydroxyapatite is non-toxic and harmless to human tissues, and will not cause immune reactions or rejection reactions.
Degradability
Hydroxyapatite can be gradually dissolved and absorbed in the human body, and will not cause foreign body reactions or rejection reactions.
Bone Tissue Regeneration
Hydroxyapatite has good biological activity and can promote bone tissue regeneration and repair damaged bones.
Modify the Surface
The groups on the surface of hydroxyapatite can be modified to promote adhesion and formation with surrounding tissues.
| Catalog Number | Product Name | Average Particle Size | Purity | Inquiry |
| ACM1306065-7 | Hydroxyapatite Powder | 200 nm | ≥ 95% | Inquiry |
| ACM1306065-23 | Hydroxyapatite Powder | 60 nm | 99.9% | Inquiry |
| ACM1306065-9 | Hydroxyapatite, Spherical-like | 2um | 96% | Inquiry |
| ACM1306065-10 | Hydroxyapatite, Spherical-like | 200nm | 95% | Inquiry |
| ACM1306065-11 | Hydroxyapatite, Needle-shaped | 60nm | 96% | Inquiry |
| ACM1306065-12 | Hydroxyapatite, Needle-shaped | 40nm | 96% | Inquiry |
| ACM1306065-13 | Hydroxyapatite, Needle-shaped | 20nm | 97.5% | Inquiry |
| ACM1306065-14 | Hydroxyapatite, Needle-shaped | 20nm | 99% | Inquiry |
| ACM1306065-15 | Hydroxyapatite, Clavate/Fibroid | 20nm | 99% | Inquiry |
| ACM1306065-16 | Hydroxyapatite, Spherical | 80um | 96% | Inquiry |
| ACM1306065-17 | Hydroxyapatite, Spherical | 15um(≤30um) | Inquiry | |
| ACM1306065-18 | Hydroxyapatite, Spherical | 50um(30-80um) | Inquiry | |
| ACM1306065-19 | Hydroxyapatite, Spherical | 100um(≥80um) | Inquiry | |
| ACM1306065-20 | Hydroxyapatite, Spherical | 200um | Inquiry | |
| ACM1306065-21 | Hydroxyapatite, Spherical | 25-45um | Inquiry | |
| ACM1306065-22 | Hydroxyapatite, Spherical | 1-3mm | Inquiry | |
| ACM1306065-24 | Hydroxyapatite Powder | 120um | Inquiry | |
| ACM1306065-25 | Hydroxyapatite Powder | ≤29um | Inquiry |
Hydroxyapatite is highly similar to the inorganic components in bones, has excellent biocompatibility, osteoconductivity and osteoinductivity, and is one of the most popular bone replacement materials.
Hydroxyapatite has a high loading capacity for some drugs, and has good biocompatibility and biodegradability, so it can be used as a drug carrier.
Hydroxyapatite can absorb organic fluorescent molecules and some luminescent genes, and is often used in bioimaging, biodiagnosis and biodetection.
Modified hydroxyapatite has the characteristics of heterogeneous catalysis and is suitable for various industrial catalytic reactions.
Hydroxyapatite has excellent biocompatibility with natural bone tissue and is considered to be the most ideal coating material for polymer and metal biomaterials.
Hydroxyapatite is also used in optical applications, oral health care, and skin repair.
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Hydroxyapatite is biocompatible as a material. It works because it’s slowly absorbed by the hydrogel carrier, and when the hydroxyapatite microspheres build up a scaffold, fibroblasts build collagen fibers on the scaffold to replace the hydrogel.
Whether biomedical (bone transplants, dental work), drug delivery, cosmetics or even medical, the reasons for choosing hydroxyapatite nanomaterials are many.
Predominant characteristics are high biocompatibility, osteoconductivity and similarity to natural bone mineral. HA nanomaterials are also mechanically strong, toxic, and may act as a promoter of cell attachment and differentiation (important in the creation of bone tissue).
Yes, you can use hydroxyapatite nanomaterials as carriers of drugs as they have high surface area and have therapeutic binding power. They can be programmed to deliver controlled drug release — for example, in bone disease and cancer.
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