Solid Phase Extraction Magnetic Beads

Product Introduction:
Solid phase extraction magnetic beads are specialized materials used for the isolation and purification of target analytes from complex sample matrices. They are widely used in various analytical chemistry applications, such as environmental analysis, pharmaceutical analysis, and clinical diagnostics.

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Background Introduction

Magnetic solid phase extraction (MSPE) is an innovative technique that utilizes a magnetic adsorbent to a solution containing a certain analyte. The analyte is adsorbed into the magnetic sorbent and subsequently separated magnetically. Finally, the analyte is eluted from the recovered adsorbent. MSPE has gained significant attention for sample preparation due to its quick and straightforward operation. Compared to traditional SPE, MSPE offers several advantages. Firstly, the magnetic adsorbents are dispersed in the solution rather than being packed into a SPE cartridge, which prevents the common issue of column blockage seen in SPE. Additionally, mass transfer of analytes can be facilitated by significantly increasing the interfacial area between adsorbent and sample solution, resulting in improved sample purification efficiency. Lastly, analytes can be separated quickly and easily without the need for centrifugation or filtration steps.

Our Products

The solid phase extraction magnetic beads provided by Alfa Chemistry are prepared by coating magnetic microspheres with a polymer material. They have the advantages of simple operation, short extraction time, less use of organic solvents, and fast solid-liquid phase separation.

Product Name	WCX Magnetic Beads	HLB Magnetic Beads	WAX Magnetic Beads
Catalog Number	NM-MBs069	NM-MBs070	NM-MBs071
Bead Size	15-50 μm	15-50 μm	15-50 μm
Specific Surface Area	700-850 m²/g	700-850 m²/g	700-850 m²/g
Pore Size	55-70 Å	55-70 Å	55-70 Å
Surface Functional Groups	Phenyl, carboxy	Phenyl, pyrrolidinone	Phenyl, piperazinyl
pH	2-10	2-10	2-10
Water Wettability	Yes	Yes	Yes
Magnetic Core	Fe₃O₄	Fe₃O₄	Fe₃O₄
Shell	Polymer	Polymer	Polymer
Appearance	Brownish solids	Brownish solids	Brownish solids
Adsorbent Substrate	Copolymer	Copolymer	Copolymer
Storage Condition	Seal and store at 0-35 °C for 24 months.

*If you have a need for other specifications, we can also provide you with product customization.

Advantages

Efficiently captures trace amounts of target analytes from sample matrices, making the separation and enrichment process simple, fast, and efficient.
Superparamagnetic and highly magnetic responsive, saving operation time.
Good dispersibility, enhancing operational convenience.
Good physicochemical stability, ensuring reproducibility of results.
Can reduce matrix effects in LC/LC-MS analysis.

You Need to Know

Before using our products, make sure to thoroughly oscillate or ultrasonic to maintain a uniform suspension of the beads.
If the analyte has strong hydrophilicity, part of the methanol in the eluent can be replaced with water to reduce potential solvent effects.
The magnetic beads have weak oxidizing properties. If the target analyte has strong reducing properties, a low concentration reducing agent such as 100 mg/L ascorbic acid solution can be added during the activation/equilibration step.
After completing the solid phase extraction steps, the sample needs to be filtered or centrifuged before performing LC/LC-MS analysis.
For best results, select and use the appropriate MSPE material for solid phase extraction.
Our products need to be used with magnetic separation equipment.
Our products are for research use only.