CdSe/ZnS QD Microspheres

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Material: CdSe/ZnS quantum dots and biocompatible polymer

Solid Content: 10 mg/mL

Zeta Potential: Approximately −40 mV

Solvent: Deionized water

Product Description

CdSe/ZnS quantum dot (QD) microspheres are advanced fluorescent materials constructed by encapsulating CdSe/ZnS quantum dots within a polymer-based microsphere matrix. In this structure, semiconductor quantum dots serve as the primary fluorescent source, while the surrounding polymer network provides a protective microenvironment that isolates the nanocrystals from external chemical and physical influences. This encapsulation strategy effectively minimizes issues such as oxidation, photobleaching, and aggregation that commonly affect free quantum dots in solution. As a result, the microsphere architecture not only preserves the intrinsic optical properties of CdSe/ZnS quantum dots but also enhances their long-term stability under various experimental conditions.

Surface Functionalization

To enable efficient bioconjugation, the surface of CdSe/ZnS QD microspheres is typically functionalized with carboxyl groups. These reactive functional groups allow the microspheres to be readily coupled with a wide range of biomolecules through standard coupling chemistries, such as carbodiimide-mediated reactions. Proteins, antibodies, peptides, and oligonucleotides can be immobilized on the microsphere surface, enabling the construction of highly specific fluorescent probes. This functional versatility makes CdSe/ZnS QD microspheres particularly valuable in bioanalytical systems.

Key Characteristics

Stable Fluorescence Signal

The CdSe/ZnS quantum dots embedded within the microspheres exhibit bright and stable fluorescence with strong resistance to photobleaching, ensuring consistent signal output during extended detection or imaging processes.

Excellent Colloidal Stability

The polymeric microsphere matrix helps maintain uniform particle dispersion in aqueous environments, effectively reducing aggregation and preserving reliable fluorescence performance in complex biological systems.

High Biocompatibility

Carefully engineered surface chemistry and material composition allow these microspheres to interact with biological molecules with minimal interference, making them suitable for a wide range of bioanalytical and diagnostic applications.

High Detection Sensitivity

Due to their strong fluorescence intensity and stable optical properties, CdSe/ZnS QD microspheres can significantly improve analytical sensitivity, enabling the detection of low-abundance targets in fluorescence-based assays.

Product Parameters

Catalog Number	Hydrodynamic Diameter	PL Emission	FWHM	Quantum Yield	Surface Carboxyl Content
NM-QD0305	50±15 nm	520±10 nm	≤25 nm	≥85%	300-360 µmol/g
NM-QD0306	50±15 nm	620±10 nm	≤28 nm	≥85%	300-360 µmol/g
NM-QD0307	100±15 nm	520±10 nm	≤25 nm	≥85%	300-360 µmol/g
NM-QD0308	100±15 nm	620±10 nm	≤28 nm	≥85%	300-360 µmol/g
NM-QD0309	150±15 nm	520±10 nm	≤25 nm	≥85%	300-360 µmol/g
NM-QD0310	150±15 nm	620±10 nm	≤28 nm	≥85%	300-360 µmol/g
NM-QD0311	200±15 nm	520±10 nm	≤25 nm	≥85%	300-360 µmol/g
NM-QD0312	200±15 nm	620±10 nm	≤28 nm	≥85%	300-360 µmol/g
NM-QD0313	400±15 nm	520±10 nm	≤25 nm	≥85%	300-360 µmol/g
NM-QD0314	400±15 nm	620±10 nm	≤28 nm	≥85%	300-360 µmol/g

*If you can't find the needed QD microspheres in the table, please send us an inquiry.

If you are looking for high-performance CdSe/ZnS QD microspheres, Alfa Chemistry is your ideal partner. Our products are carefully engineered to deliver stable fluorescence performance, excellent reproducibility, and reliable quality to meet the demands of modern bioanalytical research and assay development. Feel free to contact us for more product information and technical support.

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